Minimum:

OS: MacOS 10.12.4
Processor: Intel Core i5 (4 Cores) 3.2 GHz
Memory: 8 GB RAM
Graphics: AMD Radeon R9 M290X 2GB VRAM
Storage: 50 GB available space
Additional Notes: NOTICE: NVIDIA and INTEL video cards are NOT SUPPORTED to run Mafia III Mac
NOTICE: The game requires a minimum 2GB AMD video card. These are the ONLY supported Mac models: AMD FirePro D300, dual AMD FirePro D500, or dual AMD FirePro D700 (late 2013 MacPro) AMD Radeon R9 M290X or Radeon R9 M295X (late 2014 iMac) AMD Radeon R9 M380, M390, M395, or M395X (late 2015 iMac) AMD Radeon R9 M370X (mid 2015 and 2016 MBP) AMD Radeon Pro 450, 455, or 460 (late 2016 MBP)
NOTICE: This game is not supported on volumes formatted as Mac OS Extended (CaseSensitive)

After upgrade