Twisted Metal: Head-On is a vehicular combat video game developed by Incognito Entertainment and released by Sony Computer Entertainment on March 24, 2005 for the PlayStation Portable and February 5, 2008 for the PlayStation 2.[1] Head-On was the sixth game released in the Twisted Metal series, and the first game in the series to ship fully online-enabled.

Head-On is a direct sequel to Twisted Metal 2, ignoring the events of Twisted Metal III and Twisted Metal 4. Akin to other games in the series, Head-On revolves around the same theme of a man named Calypso holding a vehicular combat tournament called "Twisted Metal" with the promise of granting the winner whatever they ask for. In 2006, Twisted Metal: Head-On was one of the first games in the PSP Greatest Hits line in the U.S.

Twisted Metal: Head-On Extra Twisted Edition screenshots