Required:

3D hardware accelerator card required - 100% DirectX® 9.0c-compatible 64MB video card and drivers
1.2 GHz Athlon™ or 1.2 GHz Pentium® III processor or higher
384MB of RAM (512MB of RAM recommended)
Microsoft® Windows® 98/ME/2000/XP*
3.3 GB of uncompressed hard disk space for game files and saved games (plus 1.4 GB for Windows® swap file)
100% DirectX® 9.0-compatible 16-bit sound card and drivers
100% Windows® 98/ME/2000/XP-compatible mouse, keyboard, and drivers
DirectX® 9.0c

* Does not support Windows XP 64
Supported Chipsets for 98/ME/200/XP:

Vampire: The Masquerade - Bloodlines screenshots