X-change

The main character is Takuya Aihara, an average junior college student with one character flaw: he is a bit of a mental weakling. No matter how hard he tries, it seems that all the girls around him are constantly pushing him around: his teasing stepsister Natsumi, the genius president of his chemistry club Asami, and especially Asuka, his beautiful childhood friend.

One day, while cleaning some shelves in the chemistry room, he spills a mysterious chemical on himself. The next thing he knows, he is transformed into a girl. The game has seven different endings; in some Takuya remains a woman, in others he returns to being a man.